Use this calculator to determine the cost per dose for any given sterile drug product given it's
strength, vial size, vial count, preservative status, and pharmacy license. To properly calculate
the available doses, and therefore the costs, all of these factors come into play.
The results provided follow USP
797 Sterile Preparations guidance. As of this writing UPS 797 requires vials are disposed
(4) hours after puncture for preservative free compounds and (28) days for preserved compounds. This
calculator assumes that the product is within Best Use Date (BUD); USP 797 advises for disposal of
product once the BUD has been reached.
This calculator also takes into consideration the purchasing
restrictions set forth in Section
503A and Section 503B of the FD&C Act, both of which are provisions that address
requirements for the production of human drug compounds. This requires that we ask for your
patient's maximum doses in a 28 day window, as vials purchased from 503A licensed compound
pharmacies can only be administered to a single patient. Vials purchased from commercial
manufacturers or FDA recognized 503B pharmacies are assumed to be shared across patients.
When completing this form for lyophilized product you will need to enter the drug strength once
reconstituted; for example, if you had 500mg of drug product and diluted it with 5mL of
bacteriostatic water you would enter the drug strength as 100mg per every 1 mL.
per every
mL
mL